PUBLICATION

Isolation and expression analysis of foxj1 and foxj1.2 in zebrafish embryos

Authors
Aamar, E., and Dawid, I.B.
ID
ZDB-PUB-081031-4
Date
2008
Source
The International journal of developmental biology   52(7): 985-991 (Journal)
Registered Authors
Aamar, Emil, Dawid, Igor B.
Keywords
none
MeSH Terms
  • Phylogeny
  • Cilia/metabolism
  • Zebrafish Proteins/genetics*
  • Zebrafish Proteins/metabolism
  • Amino Acid Sequence
  • Forkhead Transcription Factors/genetics*
  • Forkhead Transcription Factors/metabolism
  • Molecular Sequence Data
  • Gene Expression*
  • Embryo, Nonmammalian
  • In Situ Hybridization
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Zebrafish/metabolism
  • Left-Right Determination Factors
  • Sequence Homology, Amino Acid
  • Animals
(all 17)
PubMed
18956329 Full text @ Int. J. Dev. Biol.
Abstract
In this report, we present the isolation and identification of a zebrafish homolog of the winged helix\forkhead transcription factor Foxj1. Foxj1 was identified in other species but not in zebrafish. Foxj1 was shown in mice to be required in ciliogenesis and left-right asymmetry establishment. Here we present a spatio-temporal expression pattern of zebrafish foxj1, showing that this gene is expressed in dorsal forerunner cells, Kupffers vesicle, the floor plate, pronephric ducts and kidney. This expression pattern is overlapping but different from that of the foxj1.2, the closest related gene in zebrafish. Foxj1 in zebrafish appears to have similar functions as those reported in other species connected to ciliogenesis and left-right asymmetry.
Genes / Markers
Probes
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Figures
Figure Gallery (2 images)
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Expression
Phenotype
No data available
Mutations / Transgenics
No data available
Human Disease / Model
No data available
Sequence Targeting Reagents
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Fish
Fish
WT
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Antibodies
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Orthology
Gene Orthology
foxj1a
foxj1b
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Engineered Foreign Genes
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Mapping
No data available