Gene

cct4

ID
ZDB-GENE-040426-1421
Name
chaperonin containing TCP1, subunit 4 (delta)
Symbol
cct4 Nomenclature History
Previous Names
  • zgc:65789
  • zgc:77192 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable unfolded protein binding activity. Acts upstream of or within eye morphogenesis and response to hypoxia. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is expressed in several structures, including head; immature eye; midbrain; muscle; and pectoral fin bud. Orthologous to human CCT4 (chaperonin containing TCP1 subunit 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
pc34Allele with one deletionExon 5FrameshiftCRISPR
zko1066aAllele with one deletionUnknownUnknownCRISPR
zko1066bAllele with one deletionUnknownUnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-cct4 (2)
CRISPR2-cct4Sun et al., 2019
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Human Disease
Associated With cct4 Human Ortholog
No data available
Associated With cct4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR002194 Chaperonin TCP-1, conserved site
Family IPR002423 Chaperonin Cpn60/GroEL/TCP-1 family
Family IPR012717 T-complex protein 1, delta subunit
Family IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
Family IPR053374 TCP-1 chaperonin-containing T-complex
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Domain Details Per Protein
Protein Additional Resources Length Chaperone tailless complex polypeptide 1 (TCP-1) Chaperonin Cpn60/GroEL/TCP-1 family Chaperonin TCP-1, conserved site GroEL-like apical domain superfamily GroEL-like equatorial domain superfamily T-complex protein 1, delta subunit TCP-1 chaperonin-containing T-complex TCP-1-like chaperonin intermediate domain superfamily Thermosome subunit alpha
UniProtKB:Q6PH46 InterPro 533
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 1
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cct4-201 (1) Ensembl 1,914 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cct4 monoclonal IgG Rabbit
  • IHC
  • WB
Abcam plc
2
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inFosmidCH1073-237G6ZFIN Curated Data
Contained inFosmidZFOS-663F11ZFIN Curated Data
EncodesESTIMAGE:6907982Thisse et al., 2004
EncodescDNAMGC:65789ZFIN Curated Data
EncodescDNAMGC:77192
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCCT42
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseCct411
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 11
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