Gene

cct4

ID

ZDB-GENE-040426-1421

Name

chaperonin containing TCP1, subunit 4 (delta)

Symbol

cct4 Nomenclature History

Previous Names

zgc:65789
zgc:77192 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable unfolded protein binding activity. Acts upstream of or within eye morphogenesis and response to hypoxia. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is expressed in several structures, including head; immature eye; midbrain; muscle; and pectoral fin bud. Orthologous to human CCT4 (chaperonin containing TCP1 subunit 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:65789 (1 image)
IMAGE:6907982 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cct4 Human Ortholog

No data available

Associated With cct4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002194	Chaperonin TCP-1, conserved site
Family	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family
Family	IPR012717	T-complex protein 1, delta subunit
Family	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)
Family	IPR053374	TCP-1 chaperonin-containing T-complex
Family	IPR054827	Thermosome subunit alpha
Homologous_superfamily	IPR027409	GroEL-like apical domain superfamily
Homologous_superfamily	IPR027410	TCP-1-like chaperonin intermediate domain superfamily
Homologous_superfamily	IPR027413	GroEL-like equatorial domain superfamily