Gene

bcl2l10

ID
ZDB-GENE-030825-2
Name
BCL2 like 10
Symbol
bcl2l10 Nomenclature History
Previous Names
  • mcl1l (1)
  • Boo/DIVA
  • NR-13 (1)
  • nrz (1)
  • sb:cb78
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable channel activity. Acts upstream of or within several processes, including calcium-mediated signaling; epiboly; and somitogenesis. Located in mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa23356Allele with one point mutationUnknownPremature StopENU
sa23357Allele with one point mutationUnknownPremature StopENU
sa36704Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-bcl2l10N/A (4)
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Human Disease
Associated With bcl2l10 Human Ortholog
No data available
Associated With bcl2l10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved site
Domain IPR046371 Bcl-2, Bcl-2 homology region 1-3
Family IPR002475 Bcl2-like
Family IPR026298 Bcl-2 family
Homologous_superfamily IPR036834 Bcl-2-like superfamily
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Domain Details Per Protein
Protein Additional Resources Length Apoptosis regulator, Bcl-2, BH2 motif, conserved site Bcl-2, Bcl-2 homology region 1-3 Bcl-2 family Bcl2-like Bcl-2-like superfamily
UniProtKB:Q8UWD5 InterPro PDB 176
UniProtKB:A0A8M1P8W8 InterPro 203
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 18
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bcl2l10-201 (1) Ensembl 1,349 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bcl2l10 polyclonal Rabbit
  • IHC
  • WB
2
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-235F12ZFIN Curated Data
EncodesESTcb78ZFIN Curated Data
EncodescDNAMGC:123143ZFIN Curated Data
Has ArtifactESTfb96a11ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanBCL2L1015
Amino acid sequence comparison (4)
Conserved genome location (synteny) (2)
MouseBcl2l109
Amino acid sequence comparison (3)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 23
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