Gene
bcl2l10
- ID
- ZDB-GENE-030825-2
- Name
- BCL2 like 10
- Symbol
- bcl2l10 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable channel activity. Acts upstream of or within several processes, including calcium-mediated signaling; epiboly; and somitogenesis. Located in mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb78 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Apoptosis regulator, Bcl-2, BH2 motif, conserved site | Bcl-2, Bcl-2 homology region 1-3 | Bcl-2 family | Bcl2-like | Bcl-2-like superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q8UWD5 | InterPro PDB | 176 | |||||
UniProtKB:A0A8M1P8W8 | InterPro | 203 |
1 - 2 of 2
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
bcl2l10-201
(1)
|
Ensembl | 1,349 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-bcl2l10 | polyclonal | Rabbit |
|
2 |
1 - 1 of 1
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-235F12 | ZFIN Curated Data | |
Encodes | EST | cb78 | ZFIN Curated Data | |
Encodes | cDNA | MGC:123143 | ZFIN Curated Data | |
Has Artifact | EST | fb96a11 | ZFIN Curated Data |
1 - 4 of 4
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_194398 (1) | 1363 nt | ||
Genomic | GenBank:AL935189 (2) | 170193 nt | ||
Polypeptide | UniProtKB:A0A8M1P8W8 (1) | 203 aa |
- Jones, R.A., Cooper, F., Kelly, G., Barry, D., Renshaw, M.J., Sapkota, G., Smith, J.C. (2024) Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response. Open Biology. 14:240194240194
- Ding, Q., Hao, Q., Zhang, Q., Yang, Y., Olsen, R.E., Ringø, E., Ran, C., Zhang, Z., Zhou, Z. (2022) Excess DHA Induces Liver Injury via Lipid Peroxidation and Gut Microbiota-Derived Lipopolysaccharide in Zebrafish. Frontiers in nutrition. 9:870343
- Hui, S.P., Sugimoto, K., Sheng, D.Z., Kikuchi, K. (2022) Regulatory T cells regulate blastemal proliferation during zebrafish caudal fin regeneration. Frontiers in immunology. 13:981000
- Arcanjo, C., Armant, O., Floriani, M., Cavalie, I., Camilleri, V., Simon, O., Orjollet, D., Adam-Guillermin, C., Gagnaire, B. (2018) Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages. Aquatic toxicology (Amsterdam, Netherlands). 200:114-126
- Suraweera, C.D., Caria, S., Järvå, M., Hinds, M.G., Kvansakul, M. (2018) A structural investigation of NRZ mediated apoptosis regulation in zebrafish. Cell Death & Disease. 9:967
- Hui, S.P., Sheng, D.Z., Sugimoto, K., Gonzalez-Rajal, A., Nakagawa, S., Hesselson, D., Kikuchi, K. (2017) Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs. Developmental Cell. 43:659-672.e5
- Ouyang, X., Panetta, N.J., Talbott, M.D., Payumo, A.Y., Halluin, C., Longaker, M.T., Chen, J.K. (2017) Hyaluronic acid synthesis is required for zebrafish tail fin regeneration. PLoS One. 12:e0171898
- Hu, P., Liu, M., Liu, Y., Wang, J., Zhang, D., Niu, H., Jiang, S., Wang, J., Zhang, D., Han, B., Xu, Q., Chen, L. (2016) Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish. Scientific Reports. 6:28952
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Hu, P., Liu, M., Zhang, D., Wang, J., Niu, H., Liu, Y., Wu, Z., Han, B., Zhai, W., Shen, Y., Chen, L. (2015) Global identification of the genetic networks and cis-regulatory elements of the cold response in zebrafish. Nucleic acids research. 43(19):9198-213
1 - 10 of 23
Show