Gene

oprd1b

ID
ZDB-GENE-030131-8473
Name
opioid receptor, delta 1b
Symbol
oprd1b Nomenclature History
Previous Names
  • fb12g05
  • wu:fb12g05
  • ZfDOR2 (1)
  • ZFOR4 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Enables G protein-coupled enkephalin receptor activity and morphine receptor activity. Acts upstream of or within G protein-coupled opioid receptor signaling pathway and enteric nervous system development. Located in plasma membrane. Is expressed in several structures, including central nervous system; notochord; prechordal plate; swim bladder bud; and trunk. Human ortholog(s) of this gene implicated in alcohol dependence; alcohol use disorder; drug dependence (multiple); opioid abuse; and withdrawal disorder. Orthologous to human OPRD1 (opioid receptor delta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-oprd1b
    Moreno-Campos et al., 2024
    MO1-oprd1bN/A (4)
    1 - 2 of 2
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    Human Disease
    Associated With oprd1b Human Ortholog
    No data available
    Associated With oprd1b Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR017452 GPCR, rhodopsin-like, 7TM
    Family IPR000276 G protein-coupled receptor, rhodopsin-like
    Family IPR001418 Opioid receptor
    1 - 3 of 3
    Domain Details Per Protein
    Protein Additional Resources Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Opioid receptor
    UniProtKB:B3DH72 InterPro 375
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 16
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA oprd1b-201 (1) Ensembl 2,362 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    Name Type Antigen Genes Isotype Host Organism Assay Source Citations
    Ab1-oprd1b Rabbit
    • IHC
    1
    1 - 1 of 1
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-199C22
    EncodesESTfb12g05
    EncodescDNAMGC:194047ZFIN Curated Data
    1 - 3 of 3
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanOPRD11
    Amino acid sequence comparison (4)
    Conserved genome location (synteny) (1)
    MouseOprd14
    Amino acid sequence comparison (3)
    Citations
    1 - 10 of 25
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