Gene

ncam1b

ID
ZDB-GENE-010822-2
Name
neural cell adhesion molecule 1b
Symbol
ncam1b Nomenclature History
Previous Names
  • ncam3
  • zPCAM (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Acts upstream of or within axon guidance. Predicted to be located in plasma membrane. Predicted to be active in neuron projection. Is expressed in nervous system; otic vesicle; posterior neural keel; spinal cord neural rod; and spinal cord neural tube. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; bipolar disorder; drug dependence; middle cerebral artery infarction; and nicotine dependence. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Langhauser et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ka901Allele with multiple variantsUnknownUnknownCRISPR
ka902Allele with one deletionUnknownUnknownCRISPR
la019186TgTransgenic insertionUnknownUnknownDNA
la019189TgTransgenic insertionUnknownUnknownDNA
sa35854Allele with one point mutationUnknownSplice SiteENU
sa35855Allele with one point mutationUnknownPremature StopENU
sa42522Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-ncam1bN/A (2)
MO2-ncam1bN/A (2)
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Human Disease
Associated With ncam1b Human Ortholog
No data available
Associated With ncam1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
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Domain Details Per Protein
Protein Additional Resources Length Cell Adhesion and Cytoskeletal Organization Fibronectin type III Fibronectin type III superfamily Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Neural and epithelial cell adhesion domain-containing protein Neural cell adhesion
UniProtKB:A0A8M3ASL0 InterPro 866
UniProtKB:A0A8M2B3P6 InterPro 1055
UniProtKB:A0A8M2B488 InterPro 1047
UniProtKB:A0A8M2B466 InterPro 1039
UniProtKB:A0A8M3AH81 InterPro 1044
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 15
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ncam1b-201 (1) Ensembl 3,738 nt
mRNA ncam1b-202 (1) Ensembl 961 nt
mRNA ncam1b-203 (1) Ensembl 3,738 nt
mRNA ncam1b-204 (1) Ensembl 812 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ncam1b polyclonal Rabbit
  • IHC
2
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-78D3ZFIN Curated Data
Contained inBACDKEY-85H21ZFIN Curated Data
EncodescDNAcssl:d097Bushell et al., 2007
EncodescDNAcssl:d825Bushell et al., 2007
EncodescDNAMGC:193517ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNCAM111
Conserved genome location (synteny) (2)
Amino acid sequence comparison (2)
MouseNcam19
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
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