Gene
fabp7a
- ID
- ZDB-GENE-000627-1
- Name
- fatty acid binding protein 7, brain, a
- Symbol
- fabp7a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including gill; immature eye; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human FABP7 (fatty acid binding protein 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 40 figures from 22 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66373 (38 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-fabp7a | Charlton-Perkins et al., 2019 | |
| CRISPR2-fabp7a | Charlton-Perkins et al., 2019 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein | Lipocalin/cytosolic fatty-acid binding domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q9I8N9 | InterPro | 132 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
fabp7a-203
(1)
|
Ensembl | 565 nt | ||
| mRNA |
fabp7a-201
(1)
|
Ensembl | 710 nt | ||
| mRNA |
fabp7a-202
(1)
|
Ensembl | 584 nt |
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Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-fabp7a | monoclonal | Mouse |
|
1 |
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Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(fabp7a:DsRed) |
|
| 1 | Jin et al., 2022 |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-266G18 | ZFIN Curated Data | |
| Encodes | EST | fb62f07 | ||
| Encodes | EST | fq20b08 | Rauch et al., 2003 | |
| Encodes | cDNA | MGC:66373 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192112 | ZFIN Curated Data | |
| interacts with | Promoter | fabp7a_promoter | Laprairie et al., 2017 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_131605 (1) | 700 nt | ||
| Genomic | GenBank:CU306817 (2) | 176617 nt | ||
| Polypeptide | UniProtKB:Q9I8N9 (1) | 132 aa |
- Engel-Pizcueta, C., Hevia, C.F., Voltes, A., Livet, J., Pujades, C. (2024) Her9 controls the stemness properties of hindbrain boundary cells. Development (Cambridge, England). 152(1):
- Kuil, L.E., Kakiailatu, N.J.M., Windster, J.D., Bindels, E., Zink, J.T.M., van der Zee, G., Hofstra, R.M.W., Shepherd, I.T., Melotte, V., Alves, M.M. (2023) Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level. iScience. 26:107070107070
- Mizoguchi, T., Okita, M., Minami, Y., Fukunaga, M., Maki, A., Itoh, M. (2023) Age-dependent dysfunction of the cerebrovascular system in the zebrafish telencephalon. Experimental gerontology. 178:112206
- Shainer, I., Kuehn, E., Laurell, E., Al Kassar, M., Mokayes, N., Sherman, S., Larsch, J., Kunst, M., Baier, H. (2023) A single-cell resolution gene expression atlas of the larval zebrafish brain. Science advances. 9:eade9909
- Silva, N., Campinho, M.A. (2023) In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity. Frontiers in endocrinology. 14:11576851157685
- Gao, P., Jia, D., Li, P., Huang, Y., Hu, H., Sun, K., Lv, Y., Chen, X., Han, Y., Zhang, Z., Ren, X., Wang, Q., Liu, F., Tang, Z., Liu, M. (2022) Accumulation of Lipid Droplets in a Novel Bietti Crystalline Dystrophy Zebrafish Model With Impaired PPARα Pathway. Investigative ophthalmology & visual science. 63:32
- Hsu, A.Y., Wang, T., Syahirah, R., Liu, S., Li, K., Zhang, W., Wang, J., Cao, Z., Tian, S., Matosevic, S., Staiger, C.J., Wan, J., Deng, Q. (2022) Rora Regulates Neutrophil Migration and Activation in Zebrafish. Frontiers in immunology. 13:756034
- Jin, M., Zhang, H., Xu, B., Li, Y., Qin, H., Yu, S., He, J. (2022) Jag2b-Notch3/1b-mediated neuron-to-glia crosstalk controls retinal gliogenesis. EMBO reports. 23(10):e54922
- Kouprianov, V.A., Selmek, A.A., Ferguson, J.L., Mo, X., Shive, H.R. (2022) brca2-mutant zebrafish exhibit context- and tissue-dependent alterations in cell phenotypes and response to injury. Scientific Reports. 12:883
- Hung, J.C., Wu, J.L., Hong, J.R. (2021) Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish. International Journal of Molecular Sciences. 22(9):
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