Fig. 7
- ID
- ZDB-FIG-251208-33
- Publication
- Kikuchi et al., 2025 - HoxB-derived hoxba and hoxbb clusters are essential for the anterior-posterior positioning of zebrafish pectoral fins
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hoxb4a-b5adel/del;hoxb5bdel/del larvae partially recapitulate the absence of the pectoral fins. (A–C) Dorsal views of zebrafish hoxba−/−;hoxb5bdel/del larvae at 3 dpf. (D, E) Expression patterns of tbx5a in sibling wild-type and hoxba−/−;hoxb5bdel/del (n = 4) at 30 hpf. Arrowheads indicate the presumptive positions of pectoral fin buds. (F, G) Dorsal view of frameshift-induced hoxb5a−/−;hoxb5b−/− and hoxb5adel/del;hoxb5bdel/del larvae. (H–L) Dorsal view of frameshift-induced hoxb4a−/−;hoxb5a−/−;hoxb5b−/− and hoxb4a-b5adel/del;hoxb5bdel/del larvae. All images are captured from the dorsal side. Arrowheads indicate the presumptive positions of pectoral fin buds. (M–R) Expression patterns of zebrafish hoxb4a, hoxb6a, hoxb6b, hoxb7a, hoxb8a, and hoxb8b at the 10-somite stage. Dorsal views. Arrowheads indicate the presumptive positions of pectoral fin buds. Scale bars represent 100 µm. |