FIGURE

Fig. 4

ID

ZDB-FIG-250707-66

Publication

Neelathi et al., 2025 - Variants in NR6A1 cause a novel oculo vertebral renal syndrome

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Fig. 4

Expression pattern of nr6a1a and nr6a1b paralogs in zebrafish.

nr6a1a is expressed ubiquitously at 11 hours post-fertilization (hpf) (a). By 16–19 hpf (b,c) expression is present in multiple structures including the somites (S), neural tube (NT) and notochord (N). At 24 hpf, expression remains in the NT but is decreased in the S and N. Expression in the lens (L) is first noted at 19 hpf and is particularly prominent by 24 hpf (d–d”‘’). nr6a1b expression at 11 hpf (e) is in anterior trunk, localizing to neural tube and somites from 16 hpf (f) and 19 hpf (g). At 24hpf (h–h”) it remains expressed in the neural tube and somites, with faint expression can be seen in the lens. All embryos are oriented in a lateral view, anterior to the left and dorsal up, except (d’, d”, h’, and h”) shown in dorsal views. Scale bar = 100 µm. e-epiphysis, l-lens, p-pronephros, h- heart, n-notochord, s-somite, nt-neural tube, ad-anterior diencephalon, tg-tegmentum.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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