FIGURE

Figure 8

ID

ZDB-FIG-241019-57

Publication

Wijerathna et al., 2024 - CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening

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Figure 8

Effect of UDCA treatment on the expression of bile transporters in WT and fech^−/− larvae (3 dpf) that were treated with 100 µM of UDCA and for which, after 12 and 24 h, qPCR was performed. UDCA treatment induced the expression of (A) abcb11a and (B) abcc2 to a greater extent in both WT and fech^−/− larvae compared with that in the control. RT-qPCR results are presented as the means ± SD (n = 3). Statistical significance between control and UDCA-treated fech^−/− larvae was analyzed using the Student’s t-test (ns, non-significant; **, p ≤ 0.01; ****, p ≤ 0.0001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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