FIGURE

Figure 4

ID

ZDB-FIG-240930-64

Publication

Disner et al., 2024 - TnP and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model

Other Figures

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Figure 4

Transcriptomic analysis in a zebrafish inflammation model treated with TnP. (A) Experimental design comprising Ahr2-knockdown (KD), TnP prophylactic treatment, and injury-induced inflammation model by tail fin amputation. (B) Principal component analysis (PCA) for the overall distribution of the datasets; the ellipses limit the 95% confidence interval among biological replicates. (C) Hierarchical clustering heatmap depicting gene transcription patterns; adjust p-value < 0.05 and log₂ fold change ±0.5. (D) Bar plots illustrating the differentially expressed genes (DEGs) between pairwise comparisons in both genotypes. (E) Venn diagrams of the overlapping and distinct DEGs in KD and wild-type (WT) groups modulated by TnP under inflammatory conditions.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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