FIGURE

Fig. 6

ID

ZDB-FIG-240509-39

Publication

Tucker et al., 2024 - Zebrafish raptor mutation inhibits the activity of mTORC1, inducing craniofacial defects due to autophagy-induced neural crest cell death

Other Figures

(all 15)

All Figure Page

Back to All Figure Page

Fig. 6

Loss of raptor induces neural crest cell death. (A-C) Confocal images of representative (A) wild-type, (B) heterozygous and (C) raptor mutant fish at 36 hpf. Red puncta are TUNEL-positive cells. Green cells are fli1:EGFP positive. (D) Graph of TUNEL-positive puncta in the first two pharyngeal arches. Each point is one fish: wild type (circles), heterozygote (triangles) and mutant (squares). The statistical analyses were conducted using one-way ANOVA followed by Tukey's honest significant difference (HSD) post-hoc test for multiple comparisons, **P<0.01, ***P<0.001. Data are mean±s.e.m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rptor^au93/au93; y1Tg (AB)
Observed In:	cranial neural crest cell death
Stage:	Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development