FIGURE

Fig. 4

ID

ZDB-FIG-240130-51

Publication

Kozol et al., 2023 - Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models

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Fig. 4

LiCl does not impact lights-off reactivity or activity in wildtype and shank3ab mutants. a) Activity during the first 30 seconds of lights-off of larvae exposed to 5 mM LiCl. b) Activity during the full 5 minutes lights-off of larvae exposed to 5 mM LiCl. Box plots represent 25th and 75th percentile, and median, with min to max whiskers. Sample sizes: WT = 20, WT + risperidone = 16, shank3 N = 18, shank3 N + risperidone = 18, shank3 C = 16, shank3 C + risperidone = 16. p values; * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	shank3a^{umi101/umi101}; shank3b^{umi102/umi102} (AB/TL) shank3a^{zf3839/zf3839}; shank3b^{zf3840/zf3840} (AB/TL)
Conditions:	chemical treatment by environment: lithium chloride lighting conditions
Observed In:	swimming behavior visual behavior
Stage:	Day 6

Phenotype Detail

Acknowledgments

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