FIGURE

Fig. S11

ID

ZDB-FIG-190826-3

Publication

Whitesell et al., 2019 - foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish

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Fig. S11

foxc1a and foxc1b compound mutant morphology. Lateral images at 48 hpf (A) and 96 hpf (B), showing increasing cardiovascular insufficiency (pericardial edema, hydrocephalus) with progressive loss of foxc1a/foxc1b alleles. At 48 hpf, there is little morphological difference among all genotypes, except for mild edema in foxc1a mutants. At 96 hpf, there is severe edema in foxc1a^-/-embryos, with the most severe phenotype with additional loss of foxc1b alleles. Scale bar represents 50 µm for all panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxc1a^{ua1017/ua1017} foxc1a^{ua1017/ua1017}; foxc1b^ua1018/+ foxc1a^{ua1017/ua1017}; foxc1b^{ua1018/ua1018}
Observed In:	heart
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 453(1), Whitesell, T.R., Chrystal, P.W., Ryu, J.R., Munsie, N., Grosse, A., French, C.R., Workentine, M.L., Li, R., Zhu, L.J., Waskiewicz, A., Lehmann, O.J., Lawson, N.D., Childs, S.J., foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish, 34-47, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.