FIGURE

Fig. 6

ID

ZDB-FIG-190730-35

Publication

Nord et al., 2019 - The zebrafish HGF receptor met controls migration of myogenic progenitor cells in appendicular development

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Fig. 6

The pax3a:EGFP⁺ populations of MMPs migrating out from the somites are reduced in met^-/- mutants.

Lateral view of transgenic pax3a:EGFP expression in (A) met^+/+ siblings and (B) met^-/-mutant embryos at 28 hpf (n = 6 for met^+/+ and n = 9 for met^-/-), 36 hpf (n = 7 for met^+/+and n = 5 for met^-/-) and 48 hpf (n = 5 for met^+/+ and n = 5 for met^-/-). (C) met^+/+ siblings (n = 5) and met^-/- mutant (n = 5) pax3a:EGFP (green) embryos treated with BrdU (red) from 24 to 48 hpf to visualize proliferating cells. Dashed line in A indicate yolk-somite border. Abbreviations: sh: sternohyoideus; fb: fin bud; phm: posterior hypaxial muscle. Scale bar: 50 μm.

Expression Data

Gene:	EGFP
Fish:	i150Tg met^umu7/umu7; i150Tg
Anatomical Terms:	migratory muscle precursor stream pectoral fin bud posterior hypaxial muscle sternohyoid
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	met^umu7/umu7; i150Tg
Observed In:	migratory muscle precursor pectoral fin bud pectoral fin bud cell population proliferation
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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