FIGURE

Fig. 1

ID

ZDB-FIG-180123-19

Publication

Lai et al., 2017 - Teratogenic Effects of Topiramate in a Zebrafish Model

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Under-maturation of oogenesis was shown in topiramate-treated female fish. Developmental status of oocyte in maternal fish was determined by Hematoxylin and eosin (H & E) staining. (A) Generally, the ovary was filled with mature oocytes in control fish in a high percentage; (B–F) however, a decreased percentage of mature oocytes was detected in different topiramate-treated female fish. Identification of the maturation stage was based on morphologies (I, primary growth stage; II, early cortical alveolus stage; II *, mid-cortical alveolus stage III, vitellogesis stage; IV, mature oocyte); (G) statistical analysis of oogenesis stages. Columns represent the number of cells at the four stages as percentages of the total counted (averages ± SD; *** p < 0.005; control n = 8; topiramate-treated n = 7).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical treatment by diet: topiramate
Observed In:	oocyte stage I oocyte stage III oocyte stage IV oogenesis
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.