FIGURE

Fig. 5

ID

ZDB-FIG-171228-21

Publication

Lawir et al., 2017 - A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish

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Fig. 5

Chemokine receptor expression.

(A) Representative microphotographs of wild-type and zbtb17 mutant embryos after RNA in situ hybridization with ccr9a and ccr9b gene-specific probes at 5 dpf. Insets represent 2× magnifications of the thymic regions. No signal is detectable in zbtb17 mutants. Scale bar, 100 μm. (B) Gene expression levels for ccr9a and ccr9b in zbtb17 ATG-morphants as assessed by qPCR. (C) Gene expression levels for rag1, ccr9a and ccr9b in socs1a and socs3b morphants as assessed by qPCR.

Expression Data

Genes:	ccr9a ccr9b rag1
Fish:	WT zbtb17^{t20463/t20463} TU + MO1-socs3b TU + MO1-zbtb17 TU + MO3-socs1a
Knockdown Reagents:	MO1-socs3b MO1-zbtb17 MO3-socs1a
Anatomical Terms:	thymus thymus anatomical region whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zbtb17^{t20463/t20463} TU + MO1-socs3b TU + MO1-zbtb17 TU + MO3-socs1a
Knockdown Reagents:	MO1-socs3b MO1-zbtb17 MO3-socs1a
Observed In:	thymus thymus anatomical region whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

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