FIGURE

Fig. 1

ID

ZDB-FIG-171206-65

Publication

Witzel et al., 2017 - Isl2b regulates anterior second heart field development in zebrafish

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Fig. 1

Residual Isl1/2 positive cells in isl1−/− zebrafish hearts.

(a–c) Confocal images of wild-type sibling and Tg(myl7:EGFP-HsHRAS)^s883 isl1−/− embryos stained with anti-GFP and anti-Isl1/2 antibodies at 24 somites (a), 26 hpf (b) and 48 hpf (c). Arrows point to Isl1⁺ cells at the periphery of the cone (a) or Isl1⁺ cardiomyocytes at the venous pole of the atrium (b,c), arrowheads point to residual Isl1/2⁺ cardiomyocytes in the future ventricle (a) or the inner curvature of the ventricle and the outflow pole (b,c). Scale bars, 50 μm.

Expression Data

Gene:	EGFP
Antibody:	Ab2-isl
Fish:	s883Tg isl1a^sa29/sa29; s883Tg
Anatomical Terms:	bulbus arteriosus cardiac muscle cell cardiac ventricle heart rudiment peripheral region presumptive bulbus arteriosus presumptive cardiac ventricle primitive heart tube presumptive sinus venosus cardiac muscle cell sinus venosus cardiac muscle cell (all 8)
Stage Range:	20-25 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	isl1a^sa29/sa29; s883Tg
Observed In:	heart rudiment peripheral region sinus venosus
Stage Range:	20-25 somites to Long-pec

Phenotype Detail

Acknowledgments

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