FIGURE

Fig. 6

ID

ZDB-FIG-170109-26

Publication

Takeuchi et al., 2015 - Type IV Collagen Controls the Axogenesis of Cerebellar Granule Cells by Regulating Basement Membrane Integrity in Zebrafish

Other Figures

(all 21)

All Figure Page

Back to All Figure Page

Fig. 6

BM structure is disrupted in the col4a6 mutant hindbrain.

Dorsal hindbrain of 5 dpf wild-type (A, B) and col4a6 mutant (C-F) larvae was analyzed by electron microscopy. Cross sections (A, C). (B, D) Higher-magnification views of box B in A and box D in C. (E, F) Higher-magnification images of boxes E and F in D. The BM is indicated by yellow arrowheads. Axons containing synaptic vesicles are marked by blue dashed circles. The BM was branched (E) or truncated (F) in the col4a6 mutant hindbrain. N, nucleus. Scale bars: 10 μm in A; 2 μm in B; 10 μm in C; 2 μm in D; 0.5 μm in E; 0.5 μm in F.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	col4a6^rk18/rk18
Observed In:	hindbrain basement membrane hindbrain basement membrane organization
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.