FIGURE

Fig. 3

ID

ZDB-FIG-140812-20

Publication

Wiweger et al., 2014 - Possible effects of EXT2 on mesenchymal differentiation--lessons from the zebrafish

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Fig. 3

Homozygous ext2 mutant displays musco-skeletal phenotype. Whole mount immunolocalisation at 4dpf using MF-20 antibody for muscles (green) and collagen II for cartilage (red) shows thicker and shorter muscles fitting the malformed cartilaginous skeleton in the ext2^-/- fish. Muscles: intermandibularis anterior (ima), intermandibularis posterior (imp), adductor mandibulae (am), interhyoideus (ih), hyohyoideus (hh), levator arcus palatine (lap), adductor hyoideus (ah), dilator operculi (do), sternohyoideus (sh) and adductor operculi (ao). Note missing hh muscle and, marked with a star, increased musculature around heart (H) in ext2-/-. Scale = 0.1 mm.

Expression Data

Antibody:	Ab-MF20
Fish:	WT ext2^{to273b/to273b}
Anatomical Terms:	adductor hyohyoid adductor mandibulae adductor operculi dilatator operculi hyohyoideus interhyoideus levator arcus palatini sternohyoid ventral intermandibularis anterior ventral intermandibularis posterior (all 10)
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ext2^{to273b/to273b}
Observed In:	adductor hyohyoid adductor mandibulae adductor operculi cranial cartilage dilatator operculi head muscle heart anatomical region hyohyoideus interhyoideus levator arcus palatini muscle sternohyoid ventral intermandibularis anterior ventral intermandibularis posterior (all 14)
Stage:	Day 4

Phenotype Detail

Acknowledgments

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