FIGURE

Fig. 6

ID

ZDB-FIG-140507-10

Publication

Fero et al., 2014 - Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

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Fig. 6

Slow muscle myofibrils are partially disrupted in y241 mutants. (A) F59 staining against slow-twitch muscle myosin heavy chain in 48 hpf embryos shows the presence of slow muscle fibers at the lateral edge of the somite in both mutants and siblings but disorganized thick filaments in y241 mutants. Scale bar: 20 μm. Insets show rotated transverse view through the somite. (B) α-actinin staining in slow-twitch fibers shows preserved Z-lines (arrowheads) in y241 mutants. Scale bar: 25 μm.

Expression Data

Antibodies:	Ab-F59 Ab1-actn
Fish:	dusp27^{y241Et/y241Et} (TL) dusp27^y241Et/+ (TL)
Anatomical Terms:	slow muscle cell slow muscle cell Z disc
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dusp27^{y241Et/y241Et} (TL)
Observed In:	slow muscle cell skeletal myofibril assembly slow muscle cell striated muscle myosin thick filament slow muscle cell Z disc
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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