Fig. S5
- ID
- ZDB-FIG-091221-28
- Publication
- Song et al., 2009 - Mechanisms Underlying Metabolic and Neural Defects in Zebrafish and Human Multiple Acyl-CoA Dehydrogenase Deficiency (MADD)
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xav mutants exhibit neural and glial defects and cell death. At 3 dpf, xav embryos exhibited increased cell death as assayed by TUNEL staining (green), reduced neuropil as assayed by SV2 staining (blue). Glia number and patterning as assayed by GFAP staining (red) was aberrant throughout the nervous system. Not only were glial processes irregular in shape, but clumps of GFAP+cells were observed in several brain regions (white arrowheads point to several examples). N>3 embryos, 1 carrier pair. Scale bar = 20 μm. |
Fish: | |
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Observed In: | |
Stage: | Protruding-mouth |