Fig. S2
- ID
- ZDB-FIG-081003-35
- Publication
- Caron et al., 2008 - In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis
- Other Figures
- (all 11)
- All Figure Page
- Back to All Figure Page
Blocking proliferation eliminates late-born neurons in trigeminal sensory ganglia. To remove late-born neurons from the trigeminal sensory ganglia, proliferation was blocked after 24 hpf by treating embryos with anti-proliferative drugs. (A,B) Wild-type embryos were treated with 2% DMSO alone (A) or 20 mM hydroxyurea and 150 μM aphidicolin (B). Embryos were analyzed using BAPTI at 72 hpf. Late-born neurons contain only green, unconverted, Kaede (white arrowhead), whereas early-born neurons also contain red, converted, Kaede (white arrow). (C) The chart represents the number of late-born neurons per trigeminal sensory ganglion in treated and mock-treated embryos. Late-born neurons are severely reduced or absent upon treatment with the anti-proliferative drugs. The error bar refers to the standard error. |
Gene: | |
---|---|
Fish: | |
Condition: | |
Anatomical Term: | |
Stage: | Protruding-mouth |