FIGURE SUMMARY
Title

A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome

Authors
Zhang, Y., Chen, Y., Liu, F.Y., Fu, J.W., Liu, X.X., Tan, J., Huang, O.P., Zou, Y.
Source
Full text @ Gynecol Endocrinol
Fig. 1

Representative sequencing electropherograms of the AXIN2 mutation, the arrow refers to locations of the mutation

Fig. 2

The evolutionary conservation analyses of Axin-2 mutation among 15 different vertebrates, the arginine (R)residue is highly conserved.

Fig. 3

The protein structural difference between wild type Axin-2 (p.Arg 714) and mutated Axin-2 (p.Trp 714) proteins. The protein structures of wild type and mutated Axin-2 proteins were modeled based on the crystal model of the human Axin-2 protein.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Gynecol Endocrinol
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