Genomic Features

Allele	Type	Affected Genomic Region	Affected Genomic Region
gmu1Tg	Transgenic Insertion		Tg2(lmo2:LOXP-DsRed-LOXP-EGFP)
gmu2Tg	Transgenic Insertion		Tg(lmo2:LOXP-DsRed-LOXP-hoxb4a-EGFP)

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Statement of Research Interest

Lab Members

Sun, Congjie Graduate Student

Wu, Xi-Jun Fish Facility Staff

Zhou, Yan-Hua Administrative Staff

Zebrafish Publications of lab members

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• Lv, M., Mao, X., Lu, Z., Yang, Y., Huang, J., Cheng, Y., Ye, C., He, Z., Shu, L., Mo, D. (2024) 6PPD induces cerebrovascular defects by triggering oxidative stress and ferroptosis in zebrafish. The Science of the total environment. 958:178004178004
• Cheng, T., Xing, Y.Y., Liu, C., Li, Y.F., Huang, Y., Liu, X., Zhang, Y.J., Zhao, G.Q., Dong, Y., Fu, X.X., Tian, Y.M., Shu, L.P., Megason, S.G., Xu, P.F. (2023) Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants. Cell Reports. 42:112351112351
• Sun, C.J., Hu, R.Y., Li, Z.C., Jin, L., Lu, H., He, Z.X., Shu, L.P. (2022) An engineered abcb4 expression model reveals the central role of NF-κB in the regulation of drug resistance in zebrafish. Drug development research. 83(4):927-939
• Wu, X., Yang, X., Varier, K.M., Rao, Q., Song, J., Huang, L., Huang, Y., Gajendran, B., He, Z., Yuan, C., Li, Y. (2022) Synthetic flavagline derivative 1-chloroacetylrocaglaol promotes apoptosis in K562 erythroleukemia cells through miR-17-92 cluster genes. Archiv der Pharmazie. 355(12):e2200367
• Hu, M., Varier, K.M., Li, Z., Qin, X., Rao, Q., Song, J., Hu, A., Hang, Y., Yuan, C., Gajendran, B., Shu, L., Wen, M., Li, Y., Liu, H. (2021) A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 141:111877
• Wang, S., Zhang, R.H., Zhang, H., Wang, Y.C., Yang, D., Zhao, Y.L., Yan, G.Y., Xu, G.B., Guan, H.Y., Zhou, Y.H., Cui, D.B., Liu, T., Li, Y.J., Liao, S.G., Zhou, M. (2021) Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities. European Journal of Medicinal Chemistry. 222:113573
• Wu, X.J., Williams, M.J., Kew, K.A., Converse, A., Thomas, P., Zhu, Y. (2021) Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish. Frontiers in endocrinology. 12:637691
• Zhang, R.H., Wang, S., Zhang, H., Lan, J.J., Xu, G.B., Zhao, Y.L., Wang, L., Li, Y.J., Wang, Y.L., Zhou, Y.H., Liu, J.L., Pan, W.D., Liao, S.G., Zhou, M. (2020) Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors. Bioorganic chemistry. 101:104025
• Chen, L., Xiang, W., Mo, J., Sun, C., Zhou, Y., Wu, X., He, Z. (2019) [Wnt/β-catenin signaling pathway involved in the expression and drug resistance of abcb4 gene in transgenic zebrafish induced by chemotherapeutic drugs]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 35:134-139
• Hou, S., Wang, Z., Wang, J., He, Z., Shu, L. (2016) [Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos].. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 45:620-625

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