Search Ontology:
ChEBI
DADLE
- Term ID
- CHEBI:234245
- Synonyms
-
- [D-Ala(2), D-Leu(5)]-enkephalin
- [D-Ala(2), D-Leu(5)]enkephalin
- [D-Ala(2),D-Leu(5)]enkephalin
- [D-Ala2, D-Leu5]-enkephalin
- BW 180C
- BW-180C
- BW180C
- D-Ala(2),D-Leu(5)-enkephalin
- D-Ala2, D-Leu5-enkephalin
- enkephalin-(2-D-Ala, 5-D-Leu)
- H-Tyr-D-Ala-Gly-Phe-D-Leu-OH
- H-Tyr-D-L-Ala-Gly-L-Phe-D-Leu-OH
- L-tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine
- Tyr-D-Ala-Gly-Phe-D-Leu
- Tyr-D-Ala-Gly-Phe-D-Leu-OH
- Definition
- A pentapeptide comprising of L-tyrosine, D-alanine, glycine, L-phenylalanine and D-leucine residues joined in sequence by peptide linkages. It is a synthetic delta-opioid agonist that induces hibernation, promotes survival of neurons and glial cells in the CNS, and exerts neuroprotection.
- References
-
- CAS:63631-40-3
- DrugBank:DB08856
- PMID:10675680
- PMID:10810237
- PMID:10980266
- PMID:11746737
- PMID:12388671
- PMID:12388672
- PMID:15353366
- PMID:21349267
- PMID:21551984
- PMID:21905028
- PMID:22356887
- PMID:22943142
- PMID:23436882
- PMID:25283992
- PMID:25592480
- PMID:26126577
- PMID:27232517
- PMID:30666890
- PMID:31071481
- PMID:31638217
- PMID:32549974
- PMID:32932811
- PMID:33628116
- PMID:34470528
- PMID:35599785
- PMID:36678674
- PMID:38373914
- PMID:38697767
- PMID:39312071
- PMID:39611451
- Wikipedia:DADLE
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
Phenotype
Phenotype resulting from DADLE
Phenotype where environments contain DADLE
Phenotype modified by environments containing DADLE
Phenotype affecting DADLE
Human Disease Model