Search Ontology:
ChEBI

camostat

Term ID
CHEBI:135632
Synonyms
  • 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
  • 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
  • camostat
  • camostat mesilate
  • camostatum
  • N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
(all 6)
Definition
A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
References
(all 16)
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from camostat
Phenotype where environments contain camostat
Phenotype modified by environments containing camostat
Phenotype affecting camostat
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.