Term Name:	heparan sulfate proteoglycan biosynthetic process
Synonyms:	heparan sulfate proteoglycan anabolism, heparan sulfate proteoglycan biosynthesis, heparan sulfate proteoglycan formation, heparan sulfate proteoglycan synthesis, heparan sulphate proteoglycan biosynthesis, heparan sulphate proteoglycan biosynthetic process, heparin proteoglycan biosynthetic process
Definition:	The chemical reactions and pathways resulting in the formation of heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate).
Ontology:	GO: Biological Process [GO:0015012]    QuickGO    AmiGO