Term Name: Gi/o-coupled serotonin receptor activity
Synonyms: 5-HT1 receptor activity, serotonin receptor activity, coupled via Gi/o
Definition: Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
Ontology: GO: Molecular Function [GO:0001586]    QuickGO    AmiGO

Relationships
is a type of: G protein-coupled serotonin receptor activity
inverse has_part: adenylate cyclase-inhibiting serotonin receptor signaling pathway