Term Name: double-strand break repair via homologous recombination
Synonyms: HDR, homologous recombinational repair, homology-directed repair, HRR, Rad51-dependent recombinational repair, Rhp51-dependent recombinational repair
Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Ontology: GO: Biological Process [GO:0000724]    QuickGO    AmiGO

Relationships
has parts: DNA synthesis involved in double-strand break repair via homologous recombination
is a type of: double-strand break repair recombinational repair
has subtype: double-strand break repair via break-induced replication double-strand break repair via synthesis-dependent strand annealing double-strand break repair via transcription-associated homologous recombination replication-born double-strand break repair via sister chromatid exchange
negatively regulated by: negative regulation of double-strand break repair via homologous recombination
positively regulated by: positive regulation of double-strand break repair via homologous recombination
regulated by: regulation of double-strand break repair via homologous recombination