Term Name: promyelocyte
Synonyms:
Definition: A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.
Ontology: Cell Ontology [CL:0000836]

Relationships
develops from: myeloblast
develops into: myelocyte
is a type of: granulocytopoietic cell myeloid cell myeloid lineage restricted progenitor cell nucleate cell
has subtype: basophilic promyelocyte early promyelocyte eosinophilic promyelocyte late promyelocyte neutrophilic promyelocyte
has_part: azurophil granule basophilic cytoplasm increased nucleus size nucleolus
has_plasma_membrane_part: alpha-(1,3)-fucosyltransferase FUT4 CD33 molecule
lacks_plasma_membrane_part: integrin alpha-M low affinity immunoglobulin gamma Fc region receptor III signal transducer CD24