Term Name: alpha-methyl-L-tyrosine
Synonyms: (-)-alpha-Methyl-L-tyrosine, (S)-alpha-Methyltyrosine, alpha-methyl-L-p-tyrosine, alpha-methyl-L-tyrosine, alpha-methyl-p-tyrosine, alpha-methyl-para-tyrosine, alpha-Methyltyrosine, L-alpha-Methyltyrosine, Methyltyrosine, metirosina, metirosine, metirosinum, Metyrosine
Definition: An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma.
Ontology: ChEBI [CHEBI:6912]  ( EBI )

Relationships
is a type of: L-tyrosine derivative non-proteinogenic L-alpha-amino acid
has_role: antihypertensive agent EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor