Term Name: memantine
Synonyms: 1,3-Dimethyl-5-adamantanamine, 1-Amino-3,5-dimethyladamantane, 3,5-Dimethyl-1-adamantanamine, 3,5-Dimethyl-1-aminoadamantane, 3,5-dimethyladamantan-1-amine, 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine, memantina, memantine, memantinum
Definition: A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Ontology: ChEBI [CHEBI:64312]  ( EBI )

Relationships
is a type of: adamantanes primary aliphatic amine
has_parent_hydride: adamantane
has_role: antidepressant antiparkinson drug dopaminergic agent neuroprotective agent NMDA receptor antagonist
inverse is_conjugate_acid_of: memantinium(1+)
is_conjugate_base_of: memantinium(1+)