Term Name: afatinib
Synonyms: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, afatinib, afatinibum, BIBW 2992
Definition: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer.
Ontology: ChEBI [CHEBI:61390]  ( EBI )

Relationships
is a type of: aromatic ether enamide furans monochlorobenzenes organofluorine compound quinazolines secondary carboxamide tertiary amino compound
has_role: antineoplastic agent tyrosine kinase inhibitor
inverse has_part: afatinib dimaleate