Term Name: fumagillin
Synonyms: (2E,4E,6E,8E)-10-({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]oct-6-yl}oxy)-10-oxodeca-2,4,6,8-tetraenoic acid, 2,4,6,8-decatetraenedioic acid, 4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-1-oxaspiro(2,5)oct-6-yl ester, Fugillin, fumagilina, Fumagillin, fumagilline, fumagillinum, Fumidil
Definition: A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.
Ontology: ChEBI [CHEBI:48635]  ( EBI )

Relationships
is a type of: antibiotic antifungal drug carboxylic ester dicarboxylic acid monoester meroterpenoid organooxygen heterocyclic antibiotic spiro-epoxide
has_functional_parent: (all-E)-deca-2,4,6,8-tetraenedioic acid fumagillol
has_role: angiogenesis inhibitor antibacterial drug antimicrobial agent antiprotozoal drug fungal metabolite methionine aminopeptidase 2 inhibitor
inverse is_substituent_group_from: fumagillin-2-yl group