Term Name: serotonergic antagonist
Synonyms: 5-HT antagonists, 5-hydroxytryptamine antagonists, antiserotonergic agents, serotonin antagonists, serotonin blockaders
Definition: Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Ontology: ChEBI [CHEBI:48279]  ( EBI )

Relationships
is a type of: serotonergic drug
has subtype: WAY-100635 maleate
inverse has_role: (E)-trans-miyabenol C (R,R)-tramadol (R,R)-tramadol hydrochloride (S,S)-tramadol (S,S)-tramadol hydrochloride 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 8-OH-DPAT alosetron alosetron hydrochloride amperozide amperozide hydrochloride asenapine asenapine maleate beta-casomorphin-7 (human) cariprazine cariprazine hydrochloride clomipramine clomipramine hydrochloride clopenthixol clozapine cyproheptadine cyproheptadine hydrochloride sesquihydrate dotarizine fabesetron flibanserin GR 113808 GR 127935 GR 127935 hydrochloride gramine granisetron haloperidol iloperidone iodocyanopindolol ketanserin ketanserin tartrate lurasidone lurasidone hydrochloride LY-367,265 LY-310762 LY-310762 hydrochloride mesulergine metergoline methiothepin methiothepin maleate methotrimeprazine methysergide mianserin mirtazapine N-demethylmirtazapine N-desmethylclozapine NAN 190 NAN 190 hydrobromide nefazodone olanzapine oxatomide paliperidone paliperidone palmitate palonosetron palonosetron hydrochloride picrotoxinin pimavanserin pimavanserin tartrate pimozide pindolol pipamperone pipamperone dihydrochloride pizotifen pizotifen malate pizotifen maleate promazine propiomazine quetiapine risperidone ritanserin RS 39604 RS 39604 hydrochloride SB 224289 SB 224289 hydrochloride SB-269970 hydrochloride sertindole setiptiline setiptiline maleate spiperone spiramide thiethylperazine thioridazine tramadol tramadol hydrochloride tropanyl 3,5-dimethylbenzoate tropisetron tropisetron hydrochloride vortioxetine vortioxetine hydrobromide yohimbine zhankuic acid B ziprasidone zuclopenthixol