Term Name:	MI-1148
Synonyms:	(2S)-5-carbamimidamido-2-{[(2S)-2-{[(2S)-5-carbamimidamido-2-{2-[4-(carbamimidamidomethyl)phenyl]acetamido}pentanoyl]amino}-3,3-dimethylbutanoyl]amino}-N-(4-carbamimidoylbenzyl)pentanamide, 4-(guanidinomethyl)phenylacetyl-Arg-Tle-Arg-4-amidinobenzylamide, 4-guanidinomethyl-Phac-Arg-Tle-Arg-4-amba, 4-guanidinomethyl-phenylacteyl-Arg-Tle-Arg-4-amidinobenzylamide, MI 1148, MI1148, N(2)-{[4-(carbamimidamidomethyl)phenyl]acetyl}-L-arginyl-3-methyl-L-valyl-N-(4-carbamimidoylbenzyl)-L-argininamide, N(2)-{[4-(carbamimidamidomethyl)phenyl]acetyl}-L-arginyl-3-methyl-L-valyl-N-[(4-carbamimidoylphenyl)methyl]-L-argininamide
Definition:	A tripeptide comprising of L-arginine, 3-methyl-L-valine and L-arginine joined in sequence by peptide linkages and in which the amino terminus is substituted by a [4-(carbamimidamidomethyl)phenyl]acetyl group and the carboxy terminus is substituted by a (4-carbamimidoylbenzyl)amino group. It is a highly potent inhibitor of furin endoprotease (Ki = 5.5 pM) that has anti-infectious activity.
Ontology:	ChEBI [CHEBI:167663]  ( EBI )