Term Name: G-15
Synonyms: (3aS,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline, G 15, G15
Definition: An organic heterotricyclic compound that is 3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline substituted by a 6-bromo-1,3-benzodioxol-5-yl group at position 4 (the 3aS,4R,9bR-stereoisomer). It is a high affinity and selective GPER1 receptor antagonist (Ki = 20 nM) which inhibits the anti-depressive effects of estrogen in vivo.
Ontology: ChEBI [CHEBI:156295]  ( EBI )

Relationships
is a type of: benzodioxole organic heterotricyclic compound organobromine compound
has_role: antineoplastic agent G-protein-coupled receptor antagonist