Term Name:	tideglusib
Synonyms:	4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione, NP 031112, NP-031112, NP-12, NP031112, Nypta, tideglusib, tideglusibum, Zentylor
Definition:	A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy.
Ontology:	ChEBI [CHEBI:147398]  ( EBI )