Term Name: dynasore
Synonyms: 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide, Dynamin Inhibitor I, N'-[(E)-(3,4-dihydroxyphenyl)methylene]-3-hydroxy-2-naphthohydrazide
Definition: A carbohydrazide resulting from the formal condensation of the hydrazone moiety of 3,4-dihydroxybenzaldehyde hydrazone with the carboxy group of 3-hydroxy-2-naphthoic acid. It is a cell-permeable, reversible noncompetitive inhibitor of the GTPase activity of dynamin 1 and 2 and Drp1 (mitochondrial), while exhibiting no significant effect against two other small GTPases, MxA and Cdc42.
Ontology: ChEBI [CHEBI:132754]  ( EBI )

Relationships
is a type of: catechols hydrazide hydrazone naphthols
has_functional_parent: 3-Hydroxy-2-naphthoate
has_role: EC 3.6.5.5 (dynamin GTPase) inhibitor