| ZFIN ID: ZDB-EXP-260817-3 |
Experiment Conditions Description: transection: Mauthner neuron, chemical treatment by environment: metformin
| transection: Mauthner neuron |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| chemical treatment by environment: metformin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | metformin |
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| Synonyms: | 1,1-dimethylbiguanide, dimethylbiguanide, dimethyldiguanide, LA 6023, LA-6023, metformin, metformina, metformine, metforminum, N(1),N(1)-dimethylbiguanide, N,N-dimethylbiguanide, N,N-dimethyldiguanide, N,N-dimethylguanylguanidine, N,N-dimethylimidodicarbonimidic diamide, N,N-dimethyltriimidodicarbonic diamide |
| Definition: | A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. |
| Ontology: | ChEBI [CHEBI:6801] ( EBI ) |
| Publication: | Bai et al., 2026 |
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