PUBLICATION

Expression of zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish

Authors
Schvarzstein, M., Kirn, A., Haffter, P., and Cordes, S.P.
ID
ZDB-PUB-990427-17
Date
1999
Source
Mechanisms of Development   80(2): 223-226 (Journal)
Registered Authors
Haffter, Pascal
Keywords
kreisler; valentino; basic domain leucine zipper; Maf protein; somitogenesis; myogenesis; zebrafish
MeSH Terms
  • DNA-Binding Proteins/biosynthesis
  • DNA-Binding Proteins/genetics*
  • Proto-Oncogene Proteins/genetics
  • Female
  • Sequence Alignment
  • Species Specificity
  • Gene Expression Regulation, Developmental*
  • Animals
  • Genes*
  • Mesencephalon/embryology
  • Mesencephalon/metabolism
  • Somites/metabolism*
  • Maf Transcription Factors
  • Leucine Zippers/genetics
  • Avian Proteins*
  • Nerve Tissue Proteins/biosynthesis
  • Nerve Tissue Proteins/genetics
  • Sequence Homology, Amino Acid
  • Chromosome Mapping
  • Organ Specificity
  • Neurons/metabolism
  • Mutagenesis
  • Proto-Oncogene Proteins c-maf
  • Zebrafish Proteins*
  • MafB Transcription Factor
  • Rhombencephalon/embryology
  • Rhombencephalon/metabolism
  • Oncogene Proteins*
  • Molecular Sequence Data
  • Amino Acid Sequence
  • Male
  • Mice
  • Embryo, Nonmammalian/metabolism
  • Embryo, Nonmammalian/ultrastructure
  • Zebrafish/embryology
  • Zebrafish/genetics*
  • Transcription Factors/biosynthesis
  • Transcription Factors/genetics*
  • Morphogenesis/genetics
(all 39)
PubMed
10072793 Full text @ Mech. Dev.
Abstract
We have identified Zkrml2, a novel homologue of the segmentation gene Krml/val in zebrafish (Danio rerio). Zkrml2 shows 72% and 92% identity in its basic leucine zipper domain with mouse Krml1 and zebrafish val, respectively. Zkrml2 is expressed coincident with MyoD throughout the somites starting at the three somite stage, becomes restricted to the dermomyotome, and subsequently disappears. Transient expression is also detected in the reticulospinal and oculomotor neurons. Zkrml2 maps to the Oregon linkage group 11 (Boston Linkage group 14) with no mapped zebrafish mutations nearby.
Genes / Markers
Figures
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Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
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Citation
Schvarzstein, M., Kirn, A., Haffter, P., and Cordes, S.P. (1999) Expression of zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish. Mechanisms of Development. 80(2):223-226.