PUBLICATION

Seadragon genome analysis provides insights into its phenotype and sex determination locus

Authors
Qu, M., Liu, Y., Zhang, Y., Wan, S., Ravi, V., Qin, G., Jiang, H., Wang, X., Zhang, H., Zhang, B., Gao, Z., Huysseune, A., Zhang, Z., Zhang, H., Chen, Z., Yu, H., Wu, Y., Tang, L., Li, C., Zhong, J., Ma, L., Wang, F., Zheng, H., Yin, J., Witten, P.E., Meyer, A., Venkatesh, B., Lin, Q.
ID
ZDB-PUB-210820-2
Date
2021
Source
Science advances   7(34): (Journal)
Registered Authors
Huysseune, Ann, Venkatesh, Byrappa, Witten, P. Eckhard
Keywords
none
MeSH Terms
  • Animals
  • Biological Evolution
  • Male
  • Genome
  • Female
  • Zebrafish*/genetics
  • Phenotype
  • Smegmamorpha*
(all 8)
PubMed
34407945 Full text @ Sci Adv
Abstract
The iconic phenotype of seadragons includes leaf-like appendages, a toothless tubular mouth, and male pregnancy involving incubation of fertilized eggs on an open "brood patch." We de novo-sequenced male and female genomes of the common seadragon (Phyllopteryx taeniolatus) and its closely related species, the alligator pipefish (Syngnathoides biaculeatus). Transcription profiles from an evolutionary novelty, the leaf-like appendages, show that a set of genes typically involved in fin development have been co-opted as well as an enrichment of transcripts for potential tissue repair and immune defense genes. The zebrafish mutants for scpp5, which is lost in all syngnathids, were found to lack or have deformed pharyngeal teeth, supporting the hypothesis that the loss of scpp5 has contributed to the loss of teeth in syngnathids. A putative sex-determining locus encoding a male-specific amhr2y gene shared by common seadragon and alligator pipefish was identified.
Genes / Markers
Figures
Figure Gallery (4 images)
Show all Figures
Expression
Phenotype
Fish Conditions Stage Phenotype Figure
scpp5zf3686/zf3686standard conditionsAdult
scpp5zf3686/zf3686standard conditionsAdult
scpp5zf3687/zf3687standard conditionsAdult
scpp5zf3687/zf3687standard conditionsAdult
1 - 4 of 4
Show
Mutations / Transgenics
Allele Construct Type Affected Genomic Region
zf3686
    		Small Deletion
    zf3687
      		Small Deletion
      1 - 2 of 2
      Show
      Human Disease / Model
      No data available
      Sequence Targeting Reagents
      Target Reagent Reagent Type
      scpp5CRISPR1-scpp5CRISPR
      1 - 1 of 1
      Show
      Fish
      Fish
      scpp5zf3686/zf3686
      scpp5zf3687/zf3687
      1 - 2 of 2
      Show
      Antibodies
      No data available
      Orthology
      No data available
      Engineered Foreign Genes
      No data available
      Mapping
      No data available
      Your Input Welcome
      We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
      Citation
      Qu, M., Liu, Y., Zhang, Y., Wan, S., Ravi, V., Qin, G., Jiang, H., Wang, X., Zhang, H., Zhang, B., Gao, Z., Huysseune, A., Zhang, Z., Zhang, H., Chen, Z., Yu, H., Wu, Y., Tang, L., Li, C., Zhong, J., Ma, L., Wang, F., Zheng, H., Yin, J., Witten, P.E., Meyer, A., Venkatesh, B., Lin, Q. (2021) Seadragon genome analysis provides insights into its phenotype and sex determination locus. Science advances. 7(34).