PUBLICATION

Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell

Authors

Yee, N.S., Yusuff, S., and Pack, M.

ID

ZDB-PUB-010807-13

Date

2001

Source

Genesis (New York, N.Y. : 2000) 30(3): 137-140 (Journal)

Registered Authors

Pack, Michael, Yee, Nelson S.

Keywords

none

MeSH Terms

(all 20)

PubMed

11477692 Full text @ Genesis

Abstract

Genes / Markers

Figures

Expression

Phenotype

Fish	Conditions	Stage	Phenotype	Figure
WT + MO1-pdx1	standard conditions	Long-pec	endocrine pancreas decreased functionality, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Long-pec	exocrine pancreas hypoplastic, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	acinar cell decreased amount, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	determination of digestive tract left/right asymmetry process quality, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	determination of liver left/right asymmetry process quality, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	determination of pancreatic left/right asymmetry process quality, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	digestive system positional polarity, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	endocrine pancreas decreased size, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Protruding-mouth	exocrine pancreas hypoplastic, abnormal	Fig. 1
WT + MO1-pdx1	standard conditions	Day 5	endocrine pancreas size, normal	Fig. 1

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Mutations / Transgenics

Human Disease / Model

Sequence Targeting Reagents

Fish

Antibodies

Orthology

Engineered Foreign Genes

Mapping