Biography and Research Interest

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• Kawaguchi, M., Okabe, T., Okudaira, S., Hama, K., Kano, K., Nishimasu, H., Nakagawa, H., Ishitani, R., Kojima, H., Nureki, O., Aoki, J., Nagano, T. (2020) Identification of potent in vivo autotaxin inhibitors that bind to both hydrophobic pocket and channel in the catalytic domain. Journal of medicinal chemistry. 63(6):3188-3204
• Nishioka, T., Arima, N., Kano, K., Hama, K., Itai, E., Yukiura, H., Kise, R., Inoue, A., Kim, S.H., Solnica-Krezel, L., Moolenaar, W.H., Chun, J., Aoki, J. (2016) ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Scientific Reports. 6:23433
• Nakanaga, K., Hama, K., Kano, K., Sato, T., Yukiura, H., Inoue, A., Saigusa, D., Tokuyama, H., Tomioka, Y., Nishina, H., Kawahara, A., and Aoki, J. (2014) Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. Journal of biochemistry. 155(4):235-41
• Yukiura, H., Hama, K., Nakanaga, K., Tanaka, M., Asaoka, Y., Okudaira, S., Arima, N., Inoue, A., Hashimoto, T., Arai, H., Kawahara, A., Nishina, H., and Aoki, J. (2011) Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish. The Journal of biological chemistry. 286(51):43972-83
• Clifton, J.D., Lucumi, E., Myers, M.C., Napper, A., Hama, K., Farber, S.A., Smith, A.B. 3rd, Huryn, D.M., Diamond, S.L., and Pack, M. (2010) Identification of novel inhibitors of dietary lipid absorption using zebrafish. PLoS One. 5(8):e12386
• Hama, K., Provost, E., Baranowski, T.C., Rubinstein, A.L., Anderson, J.L., Leach, S.D., and Farber, S.A. (2009) In vivo imaging of zebrafish digestive organ function using multiple quenched fluorescent reporters. American journal of physiology. Gastrointestinal and liver physiology. 296(2):G445-G453
• Ouyang, M., Garnett, A.T., Han, T.M., Hama, K., Lee, A., Deng, Y., Lee, N., Liu, H.Y., Amacher, S.L., Farber, S.A., and Ho, S.Y. (2008) A web based resource characterizing the zebrafish developmental profile of over 16,000 transcripts. Gene expression patterns : GEP. 8(3):171-180

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Non-Zebrafish Publications