ZFIN Morpholino: MO2-cdx1a

Target Location

Genome Build: GRCz11Chromosome: 14

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-cdx1a

No data available

Phenotype

Phenotype resulting from MO2-cdx1a

No data available

Phenotype of all Fish created by or utilizing MO2-cdx1a

Phenotype	Fish	Conditions	Figures
lateral plate mesoderm tbx5a expression increased distribution, abnormal	cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)	standard conditions	Fig. 5 from Lengerke et al., 2011
pronephric glomerulus bilateral, abnormal	cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)	standard conditions	Fig. 5 , Fig. 7 from Wingert et al., 2007
pronephric podocyte unfused from pronephric podocyte, abnormal	cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)	standard conditions	Fig. 5 , Fig. 7 from Wingert et al., 2007
posterior pronephric duct aplastic, abnormal	cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)	standard conditions	Fig. 5 from Wingert et al., 2007
corpuscles of Stannius increased size, abnormal	cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)	chemical treatment: 4-(diethylamino)benzaldehyde	Fig. 7 from Wingert et al., 2007

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Citations

Include unpublished citations

Paik, E.J., Mahony, S., White, R.M., Price, E.N., Dibiase, A., Dorjsuren, B., Mosimann, C., Davidson, A.J., Gifford, D., and Zon, L.I. (2013) A cdx4-sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1(5):425-436
Lengerke, C., Wingert, R., Beeretz, M., Grauer, M., Schmidt, A.G., Konantz, M., Daley, G.Q., and Davidson, A.J. (2011) Interactions between Cdx genes and retinoic acid modulate early cardiogenesis. Developmental Biology. 354(1):134-142
Pillay, L.M., Forrester, A.M., Erickson, T., Berman, J.N., and Waskiewicz, A.J. (2010) The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis. Developmental Biology. 340(2):306-317
Flores, M.V., Hall, C.J., Davidson, A.J., Singh, P.P., Mahagaonkar, A.A., Zon, L.I., Crosier, K.E., and Crosier, P.S. (2008) Intestinal Differentiation in Zebrafish Requires Cdx1b, a Functional Equivalent of Mammalian Cdx2. Gastroenterology. 135(5):1665-1675
Wingert, R.A., Selleck, R., Yu, J., Song, H.D., Chen, Z., Song, A., Zhou, Y., Thisse, B., Thisse, C., McMahon, A.P., and Davidson, A.J. (2007) The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros. PLoS Genetics. 3(10):1922-1938
Davidson, A.J., and Zon, L.I. (2006) The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Developmental Biology. 292(2):506-518

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