Morpholino

MO6-pax8

ID
ZDB-MRPHLNO-050208-1
Name
MO6-pax8
Previous Names
  • variant 1 MO (1)
Target
Sequence
5' - GTTCACAAACATGCCTCCTAGTTGA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
translation blocker for splice variant 1 (variant 1 MO). This MO blocks translation of variant 1 isoforms, which lack the N-terminal Paired domain.
Reference: Mackereth et al. (2005)
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 5
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO6-pax8
No data available
Phenotype
Phenotype resulting from MO6-pax8
Phenotype Fish Figures
otic vesicle decreased size, abnormal WT + MO6-pax8 Fig. 3 with image from Porreca et al., 2012
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Phenotype of all Fish created by or utilizing MO6-pax8
Phenotype Fish Conditions Figures
otic vesicle decreased size, abnormal AB + MO6-pax8 + MO7-pax8 standard conditions Fig. 2 with image from Padanad et al., 2011
otic vesicle decreased size, abnormal WT + MO6-pax8 standard conditions Fig. 3 with image from Porreca et al., 2012
otic vesicle has fewer parts of type hair cell, abnormal WT + MO6-pax8 + MO7-pax8 standard conditions Fig. 3 with image from Mackereth et al., 2005
otic vesicle decreased size, abnormal WT + MO6-pax8 + MO7-pax8 standard conditions Fig. 2 with image,  Fig. 3 with image from Mackereth et al., 2005
midbrain hindbrain boundary decreased width, abnormal WT + MO6-pax8 + MO7-pax8 standard conditions Fig. 2 with image from Mackereth et al., 2005
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Citations
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