ZFIN Image: Bellitto et al., 2025, Fig. 5

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Figure Caption

Fig. 5 (a) Scatterplot showing the most significant GO terms emerging from proteomic analysis at 10 dpf in the zebrafish Tg(gfap:hGFAP(R239C)-GFP) larvae compared to Tg(gfap:GFP)mi2001 controls. (b) Scatterplot showing the most significant GO terms emerging from proteomic analysis of 20-dpf Tg(gfap:hGFAP(R239C)-GFP) and Tg(gfap:GFP)mi2001 larvae. Analysis was performed with Revigo, which uses Multidimensional Scaling (MDS) to reduce the dimensionality of a matrix of the GO terms pairwise semantic similarities. The resulting projection may be highly nonlinear. Connected similar GO terms remain close together in the plot; the semantic space units have no intrinsic meaning. Bubble color indicates the p-value for the false discovery rates; circle size indicates the frequency of the GO term in the underlying GO database, where bubbles of more general terms are larger.

Acknowledgments

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