ZFIN Image: Ono et al., 2024, Figure 8.

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Figure Caption

Figure 8. The excitability of LES afferents was not significantly affected by Gpr156 deletion.

Exemplary voltage responses of control (A) and null (B) afferents to injected steps of current. We recorded from the large calyceal endings as a way to access these dimorphic afferents, which, like most LES afferents, made contact with both type I and type II HCs. For current steps (bottom) at 3×I_thresh (×3, green), both genotypes produced sustained firing, considered typical of regular afferents innervating LES and MES. Here I_thresh (blue trace) was 100 pA for Gpr156^del/+ afferent and 250 pA for Gpr156^del/del afferent, but overall there was no significant difference in current threshold with genotype.

Acknowledgments

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