Fig. 3 Retinoid profiles of Zcrdh-mutant and wild-type zebrafish eyes under different light-exposure conditions Whole-eye retinoid profiles of age-matched Zcrdh-mutant (red) and AB wild-type (blue) adult zebrafish (5 months old) under different light-exposure conditions: DA, overnight dark-adapted; bleached, immediately following an ∼50% photobleach; bleach + 5, 30, or 60 min DA, bleached followed by the indicated period of recovery in the dark. (A) 11cRAL chromophore levels in the eyes of wild-type or Zcrdh-mutant zebrafish after indicated light exposures. (B) 11cROL levels in the eyes of wild-type or Zcrdh-mutant zebrafish after indicated light exposures. (C) 11cRP levels in the eyes of wild-type or Zcrdh-mutant zebrafish after indicated light exposures. Error bars show standard deviation of the mean for four replicates (n = 4).
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