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Publication: Van Schoor et al., 2024 - TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish
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FIGURE 1

ALS post-mortem motor cortex exhibits TUBA4A downregulation. (a) Western blot on SDS-soluble lysates derived from the motor cortex of control (n = 5) and ALS (n = 5) cases using an antibody against TUBA4A (C-term). GAPDH was used as a loading control. (b) Quantification of the expression of TUBA4A as a ratio to GAPDH in the motor cortex. Unpaired t-test. (c) Immunohistochemical staining of the motor cortex of a representative ALS and control case with an antibody against TUBA4A (C-term). Scale bar represents 50 μm. **p < 0.01.

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